Otrivin Metered Dose Nasal Spray effectively relieves nasal congestion within 2 minutes. Quickly provides a sensation of improved nasal airflow with long-lasting relief. Otrivin 0.1% Nasal Drops contains the active ingredient, Xylometazoline hydrochloride, which unblocks your nose by reducing swelling of the mucosa. It also helps sinus drainage so mucus can be drained out, easing painful sinus pressure. How to Use 1. Clear your nose. 2. Lean forward slightly and insert the nozzle into a nostril. 3. Spray and breathe in gently through the nose at the same time. 4. Repeat for the other nostril.